ATMP / CGT Training in NIBRT

Tandem staff recently completed NIBRT’s ATMPs/CGT Training Course. Held over two days, the training was divided between classroom learning and practical sessions.

NIBRT delivered a solid grounding in the basics of ATMPs and CGTs and their advantages over existing treatments as well as the challenges that exist in manufacturing. The training then continued to offer deeper understanding of how these treatments provide benefit to the patients, their delivery methods, and their manufacturing process.

The practical sessions allowed trainees to apply the theory to a laboratory environment and demonstrated the entire process of scaling up cells from Cell Culture to Final Downstream Purification. The sessions delivered hands on experience of processes to simulate growing cells from cell culture through scale up in a Rocker up to a Stirred Tank reactor. Trainees then set up Downstream Bioprocessing equipment including Chromatography columns, Depth Filtration and UF/DF Skids to simulate the complete purification process.

The NIBRT ATMPs/CGT Training Course was hugely beneficial to the trainees, the skills and knowledge learned will enhance their future project work.

Cork Chamber Large Company of the Year Finalist

Tandem is thrilled to be selected as a finalist in the 2021 Cork Chamber Company of the Year Awards.  To receive this recognition from the Chamber is a great honour and we are privileged to be counted amongst the finalists.


Congratulations to all of the finalists, we look forward to the ceremony on the 26th of May.

Spotlight on Services: Project Controls

The Tandem Project Controls team provides specialised expertise across project lifecycles to reduce client risk, improve value and deliver positive outcomes in all sectors of the built environment. Services include cost control, procurement, contract administration, risk management, scheduling and document control.

Through cost estimates Tandem will establish project viability and a robust baseline. It delivers value management and value engineering, lifecycle costing and cost forecasting. Tandem will estimate and plan costs to proactively manage the project budget, optimising cost performance from inception to completion. Tandem delivers and manages cost reports throughout the project lifecycle and manages cash flow forecasting.

Tandem will expertly schedule each phase of a project from concept, engineering, procurement, construction, commissioning through to qualification, validation and operational readiness.  It delivers man-loaded schedules and S-Curves with weekly earned versus actual progress reporting. Tandem’s critical path analysis, progress updates, identification of slippage and development of recovery plans delivers clarity and transparency. Tandem develops portfolio scheduling for PMO’s and micro-schedules for complex areas of work where detailed coordination is required.

Tandem offer procurement services and will prepare tender packages for trade contractors and equipment vendors, it will perform tender walkdowns and lead bid clarification meetings. Tandem will undertake commercial and technical bid analysis, issuing award recommendations on tender reports, managing vendors and leading final negotiations.

Tandem will identify the most appropriate procurement and contracting strategies to minimise risk to time, cost and quality. It will prepare contractual documentation, ensuring all parties are familiar with their contractual obligations and remain compliant at all times. Tandem employs timely communication to ensure the smooth progression of the contract. Tandem will implement change management procedures that facilitate well informed decisions and ensure effective financial management. It will deliver certification of monthly valuations, assessment and agreement of contractual claims, assessment of contractor claims for delays and provide advice when assessing claims for any time extensions and costs for delays.

Tandem’s expertise in risk management delivers analysis of potential project risks. Tandem will develop risk mitigation strategies, maintain a Risk Register and regularly communicate the mitigation status with stakeholders. Tandem also implement controlled processes and practices for the creation, review, modification, issuance, distribution and accessibility of documents.

Active Pharmaceutical Ingredients (APIs) Capabilities

Ireland is the location of choice for over 90% of the world’s top pharmaceutical companies & has become the eighth largest producer & the fifth largest exporter of pharmaceuticals. Pharmaceuticals make up 50% of all of Ireland’s manufactured exports, with Active Pharmaceutical Ingredients (APIs) forming the backbone of the sector.

Tandem’s team bring a wealth of experience to delivering successful project outcomes. Its Project Managers, Project Controllers, Design Engineers, Construction Managers & CQV Specialists have extensive life-sciences experience, having worked with many of the top API companies. This expertise allows our clients to deliver consistent controlled manufacturing to required standards.

Tandem delivers expertise to your entire project life cycle in all areas of design including process, process architecture, equipment, facility, cleanroom, clean & black utilities, HVAC & building services, electrical & instrumentation, process automation & building management systems. We also provide specialist Health & Safety services, such as Risk Assessments, HAZOP, ATEX/ EPD, pFMEA, & the full range of construction safety requirements, including BCAR Certification, PSDP & PSCS.

Biopharma Capabilities

The biopharmaceutical industry has made a capital investment of more than $10bn in new facilities in Ireland, most of which has come in the last 10 years. These facilities are technologically diverse in manufacturing drug substance and drug product.

At Tandem we have a team of Project Managers, Design Engineers, Construction Managers and CQV Engineers with extensive drug substance and drug product experience who have worked in some of the top Biopharma companies in the world and have brought that wealth of experience to delivering key projects for our clients.

We provide expertise in the areas of equipment specification and design of facility and cleanroom, clean and black utilities, HVAC, electrical, instrumentation and process automation to ensure consistent controlled manufacturing to the required quality standards.

Tandem can offer a full life-cycle package from overall project management, concept and basis of design, detailed design, (including process equipment specification and procurement), construction management, commissioning, qualification, and validation right through to operational readiness for commercial operations.

Oral Solid Dose Capabilities

Oral Solid Dosage (OSD) facilities, producing tablets & capsules, use well defined unit operations, regardless of production volumes or usage for single or multiple product manufacture. Facilities typically include Dispensing/Formulation; Blending; Granulation; Drying; Compression/Encapsulation; Coating; Packaging & Receiving/Warehousing Operations.

All OSD facility full life cycle project requirements can be designed & managed by Tandem’s team of Project Managers, Design Engineers, Construction Managers & CQV Engineers with extensive OSD experience.

Tandem will expertly deliver your desired project outcomes in Facility & Cleanroom design, Clean & Black utility design, HVAC design, OSD equipment unit operations including clean support process areas for quick turnaround without unacceptable risk of product exposure (i.e., dust & cross-contamination), Primary & Secondary Packaging operations, Serialisation & Warehouse design.

Tandem also deliver expertise in ATEX & process safety to ensure correct containment requirements are outlined & embedded in the design process.  Our building services engineers provide extensive experience in BMS/EMS systems to support the monitoring of critical processes within an OSD facility.

Fill Finish (Aseptic Processing)

Fill Finish operations (Aseptic Processing) are an essential element of the pharmaceutical and biopharmaceutical supply chain. The ability to safely, efficiently and robustly produce some of the world’s leading therapeutics in an aseptic manner is critical to the supply of life changing therapies throughout the world.

At Tandem we have a team of Project Managers and Engineers with extensive Fill Finish experience who specialise in the delivery of Aseptic processing projects.

We provide leading expertise in the areas of Fill Finish Facility and Cleanroom design (including GMP design reviews), Clean and Black utility design, HVAC design including Isolator Technology, Vial, Syringe, and Cartridge Filling and Closing, Lyophilisation, Barrier/Containment Technology (Isolators/RABS), Parts Washing and Autoclaving, Formulation and Compounding, CIP/SIP systems, and Ready to Use Single Use Systems. We also provide expertise in Process Automation systems required within Fill Finish facilities.

Tandem delivers these services throughout the entire project life cycle and can offer a full turnkey package from overall Project Management, Concept Design, Detailed Design, (including process equipment specification and procurement), Construction Management, Commissioning, Qualification, and Validation right through to Operational Readiness.